Concepedia

Acquisition of p53 mutations in response to the non-genotoxic p53 activator Nutlin-3

Moammir Hasan Aziz, Haitao Shen, Carl G. Maki

Oncogene · 2011 · 133 citations · 26 references

DOIFull text

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Concepts

References

26

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

, , +15

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

, , +10

p53 Has a Direct Apoptogenic Role at the Mitochondria

Motohiro Mihara, Susan Erster, Alexander Zaika et al. · Molecular Cell · 2003 · 1.8K citations · Full text

, , +12

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells.

Warren Maltzman, Linda Czyzyk · Molecular and Cellular Biology · 1984 · 862 citations · Full text

, , +12