Concepedia

p53-Dependent apoptosis in the absence of transcriptional activation of p53-target genes

Carmé Caelles, Arno Helmberg, Michael Karin

Nature · 1994 · 847 citations · 27 references

DOI

Concepts

References

27

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

, , +13

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

A H Wyllie · Nature · 1980 · 4.5K citations

, , +14

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

, , +13

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

, , +12