Concepedia

Antimicrobial Peptide LL-37 is Upregulated in Chronic Nasal Inflammatory Disease

Seon Tae Kim, Heung Eog, Dong Young Kim, Gyu Cheol Han, Yoo‐Sam Chung, Jae Lee Young, You Jin Hwang, Heung-Man Lee

Acta Oto-Laryngologica · 2003 · 63 citations · 11 references

DOI

Abstract

We suggest that LL-37 is one of the antimicrobial peptides found in human nasal mucosa and that it participates in the innate immune system of the nasal mucosa.

References

11

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

Shizuo Akira, Hiroshi Isshiki, Takahisa Sugita et al. · The EMBO Journal · 1990 · 1.5K citations · Full text

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Ll-37, the Neutrophil Granule–And Epithelial Cell–Derived Cathelicidin, Utilizes Formyl Peptide Receptor–Like 1 (Fprl1) as a Receptor to Chemoattract Human Peripheral Blood Neutrophils, Monocytes, and T Cells

De Yang, Qian Chen, Albert P. Schmidt et al. · The Journal of Experimental Medicine · 2000 · 1.2K citations · Full text

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The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory Disorders

Margareta Frohm, Birgitta Agerberth, Ghasem Ahangari et al. · Journal of Biological Chemistry · 1997 · 788 citations · Full text

The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface

Robert Bals, Xiaorong Wang, Michael Zasloff et al. · Proceedings of the National Academy of Sciences · 1998 · 738 citations · Full text

The Human Gene <i>FALL39</i> and Processing of the Cathelin Precursor to the Antibacterial Peptide LL‐37 in Granulocytes

Guðmundur H. Guðmundsson, Birgitta Agerberth, Jacob Odeberg et al. · European Journal of Biochemistry · 1996 · 576 citations · Full text

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