Hiroshi Isshiki

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

Shizuo Akira, Hiroshi Isshiki, Takahisa Sugita et al. · The EMBO Journal · 1990 · 1.5K citations · Full text

Inflammation, Cytokine, Transcriptional Regulation +8

Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6

Shunji Natsuka, Shizuo Akira, Yukihiro Nishio et al. · Blood · 1992 · 297 citations · Full text

Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene.

Hiroshi Isshiki, Shizuo Akira, Osamu Tanabe et al. · Molecular and Cellular Biology · 1990 · 283 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +18

A Nuclear Factor for Interleukin-6 Expression (NF-IL6) and the Glucocorticoid Receptor Synergistically Activate Transcription of the Rat α1-Acid Glycoprotein Gene via Direct Protein-Protein Interaction

Yukihiro Nishio, Hiroshi Isshiki, Tadamitsu Kishimoto et al. · Molecular and Cellular Biology · 1993 · 211 citations · Full text

Immunology, Immune Regulation, Direct Protein-protein Interaction +24

Reciprocal expression of NF-IL6 and C/EBP in hepatocytes: possible involvement of NF-IL6 in acute phase protein gene expression.

Hiroshi Isshiki, Shizuo Akira, Takahisa Sugita et al. · PubMed · 1991 · 86 citations

Immunology, Immune Regulation, Pathology +19