Unexpected rearrangement during biomimetic entry toward a taxane skeleton

Total synthesis of taxol

K. C. Nicolaou, Zhen Yang, Jimei Liu et al. · Nature · 1994 · 1.1K citations

Natural Sciences, Biochemistry, Chemistry +5

Chemistry and Biology of Taxol

K. C. Nicolaou, Wei‐Min Dai, R. Kiplin Guy · Angewandte Chemie International Edition in English · 1994 · 620 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

First total synthesis of taxol. 2. Completion of the C and D rings

Robert A. Holton, Hyeong Baik Kim, Carmen Somoza et al. · Journal of the American Chemical Society · 1994 · 524 citations

Natural Sciences, Chemistry, Analytical Chemistry +8

An efficient algorithm for searching low-energy conformers of cyclic and acyclic molecules

Eiji O̅sawa · Journal of the Chemical Society Perkin Transactions 2 · 1993 · 414 citations

Natural Sciences, Chemistry, Computational Chemistry +11

Efficacious modification of the mitsunobu reaction for inversions of sterically hindered secondary alcohols

Stephen F. Martin, Jeffrey A. Dodge · Tetrahedron Letters · 1991 · 357 citations

Natural Sciences, Chemistry, Medicinal Chemistry +2