Concepedia

Molecular Skeleton Modification

Molecular Skeleton Modification is a computational strategy in scaffold hopping that entails the systematic alteration of a molecule's core framework while preserving essential pharmacophoric features to generate novel chemotypes with retained biological activity.

105

Publications

5.4K

Citations

599

Authors

212

Institutions

Publications per year

2017–2026

58

Parents

Publications

105

Late-stage diversification of indole skeletons through nitrogen atom insertion

Julia C. Reisenbauer, Ori Green, Allegra Franchino et al. · Science · 2022 · 375 citations · Full text

, , +15

Scaffold hopping by net photochemical carbon deletion of azaarenes

Jisoo Woo, Alec H. Christian, Samantha A. Burgess et al. · Science · 2022 · 262 citations · Full text

, , +17

Highly Emissive Organic Single‐Molecule White Emitters by Engineering <i>o</i>‐Carborane‐Based Luminophores

Deshuang Tu, Pakkin Leong, Song Guo et al. · Angewandte Chemie International Edition · 2017 · 254 citations

, , +9

Molecular Complexity via C–H Activation: A Dehydrogenative Diels–Alder Reaction

Erik M. Stang, M. Christina White · Journal of the American Chemical Society · 2011 · 169 citations

, , +15

Hydrogen evolution reaction catalyzed by ruthenium ion-complexed graphitic carbon nitride nanosheets

Yi Peng, Bingzhang Lu, Limei Chen et al. · Journal of Materials Chemistry A · 2017 · 149 citations

, , +16

1–5 of 105

Authors

599

  1. HF
    Hui Feng

    Zhejiang Normal University, China

    2 publications · 104 citations

    2

    h-index

  2. PL
    Pakkin Leong

    Nanjing University of Posts and Telecommunications, China

    2 publications · 301 citations

    2

    h-index

  3. PK
    Prasanta Kumar Das

    Indian Association for the Cultivation of Science, India

    2 publications · 137 citations

    2

    h-index

  4. JF
    Jian Fan

    Soochow University, China

    2 publications · 114 citations

    2

    h-index

  5. MK
    Motomu Kanai

    The University of Tokyo, Japan

    2 publications · 81 citations

    2

    h-index

1–5 of 599

Institutions

212

  1. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    17 publications

    726 citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    5 h-index

    14 publications

    384 citations

  3. Nankai University

    Tianjin, China

    5 h-index

    9 publications

    536 citations

  4. Nanjing University

    Nanjing, China

    4 h-index

    11 publications

    1.3K citations

  5. Soochow University

    Suzhou, China

    4 h-index

    16 publications

    625 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    12 publications

    264 citations

  7. The University of Tokyo

    Tokyo, Japan

    3 h-index

    9 publications

    462 citations

  8. Northeast Normal University

    Changchun, China

    3 h-index

    15 publications

    866 citations

1–8 of 212

Venues

  1. Journal of the American Chemical Society

    JACS · 10 publications · 829 citations

    10

    h-index

  2. The Journal of Organic Chemistry

    JOC · 7 publications · 211 citations

    7

    h-index

  3. Tetrahedron Letters

    5 publications · 129 citations

    5

    h-index

  4. Angewandte Chemie International Edition

    4 publications · 426 citations

    4

    h-index

  5. Accounts of Chemical Research

    4 publications · 214 citations

    4

    h-index

1–5