Potentiation of radiation response in human carcinoma cells in vitro and murine fibrosarcoma in vivo by topotecan, an inhibitor of DNA topoisomerase I

DNA Topoisomerase I—Targeted Chemotherapy of Human Colon Cancer in Xenografts

Beppino C. Giovanella, John S. Stehlin, Monroe E. Wall et al. · Science · 1989 · 647 citations

Medicine, Oncology, Pharmacology +15

Repair of Potentially Lethal Damage in X-Irradiated HeLa Cells¹

R. A. Phillips, L. J. Tolmach · Radiation Research · 2012 · 408 citations

Medicine, Cell Biology, Oncology +12

Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.

Connie Holm, Joseph M. Covey, Donna Kerrigan et al. · PubMed · 1989 · 370 citations

Life Sciences, Cell Biology, Apoptosis +13

DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues.

Y H Hsiang, Leroy F. Liu, Monroe E. Wall et al. · PubMed · 1989 · 341 citations

Medicine, Oncology, Pharmacology +13

Repair of Potentially Lethal Damage in X-Irradiated HeLa Cells

R. A. Phillips, L. J. Tolmach · Radiation Research · 1966 · 313 citations

Medicine, Cancer Biology, Cell Biology +14