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Characterization of the Folding Energy Landscapes of Computer Generated Proteins Suggests High Folding Free Energy Barriers and Cooperativity may be Consequences of Natural Selection

Computer Generated ProteinsProtein AssemblyProtein FoldingNatural SciencesDirected EvolutionComputational BiologyProtein EvolutionMolecular BiologyNatural SelectionStructural BiologyProtein ModelingProtein EngineeringFolding Energy LandscapesSystems BiologyMedicineBiophysicsComputational Biophysics