Synthesis and evaluation of new protein-tyrosine kinase inhibitors. Part 1. pyridine-containing stilbenes and amides.

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

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Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Towia A. Libermann, Harris R. Nusbaum, Nissim Razon et al. · Nature · 1985 · 1.5K citations

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Tyrosine Kinase Activity and Transformation Potency of <i>bcr-abl</i> Oncogene Products

T G Lugo, Ann Marie Pendergast, Alexander J. Muller et al. · Science · 1990 · 1.3K citations

Medicine, Molecular Biology, Oncology +14

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

Aviv Gazit, Pnina Yaish, Chaim Gilon et al. · Journal of Medicinal Chemistry · 1989 · 605 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7