Concepedia

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

Birgit Knoechel, Justine E. Roderick, Kaylyn E. Williamson, Jiang Zhu, Jens G. Lohr, Matthew J. Cotton, Shawn Gillespie, Daniel E. Fernandez, Manching Ku, Hongfang Wang,

Nature Genetics · 2014 · 382 citations · 37 references

DOIFull text

Open access

Concepts

References

37

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

, , +12

An integrated encyclopedia of DNA elements in the human genome

Nature · 2012 · 19.4K citations · Full text

, , +16

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.6K citations

, , +16

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.3K citations · Full text

, , +16

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

, , +5