Involvement of the Post-Transcriptional Regulator Hfq in Yersinia pestis Virulence

Abstract

Our results indicate that Hfq is a key regulator involved in Y. pestis stress resistance, intracellular survival and pathogenesis. It appears that Hfq acts by controlling the expression of many virulence- and stress-associated genes, probably in conjunction with small noncoding RNAs.