Concepedia

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Jonathan J. Halloran, Stacy A. Hussong, Raquel R Burbank, Natalia Podlutskaya, K.E. Fischer, Lauren Sloane, Steven N. Austad, Randy Strong, Arlan Richardson, Matthew J. Hart,

Neuroscience · 2012 · 221 citations · 33 references

DOI

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33

Developments of a water-maze procedure for studying spatial learning in the rat

Richard Morris · Journal of Neuroscience Methods · 1984 · 7.2K citations

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

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Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

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Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Patricia Spilman, Natalia Podlutskaya, Matthew J. Hart et al. · PLoS ONE · 2010 · 1K citations · Full text

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Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

Antonella Caccamo, Smita Majumder, Arlan Richardson et al. · Journal of Biological Chemistry · 2010 · 878 citations · Full text

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