Strategies for advancing cancer nanomedicine

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells

Devika B. Chithrani, Arezou A. Ghazani, Warren C. W. Chan · Nano Letters · 2006 · 4.8K citations

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Renal clearance of quantum dots

Hak Soo Choi, Wenhao Liu, Preeti Misra et al. · Nature Biotechnology · 2007 · 4.4K citations · Full text

Pharmacy, Nephrology, Renal Pathophysiology +6

Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

Sunil Verma, David Miles, Luca Gianni et al. · New England Journal of Medicine · 2012 · 3.8K citations · Full text

Medicine, Oncology, Pharmacology +14

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

Harold F. Dvorak, Lawrence F. Brown, Michael Detmar et al. · PubMed · 1995 · 3.1K citations

Veterinary Medicine, Physiology, Tumor Microenvironment +9