Concepedia

Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs

Thais Federici, J S Taub, Griffin R. Baum, Steven J. Gray, Joshua C. Grieger, Kristin A Matthews, Chalonda R. Handy, Marco A. Passini, R. Jude Samulski, Nicholas M. Boulis

Gene Therapy · 2011 · 166 citations · 39 references

DOI

Concepts

References

39

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

Kevin D. Foust, Emily Nurre, Chrystal L. Montgomery et al. · Nature Biotechnology · 2008 · 1.4K citations · Full text

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Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao Xiao, Juan Li, R. Jude Samulski · Journal of Virology · 1998 · 1.4K citations · Full text

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Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

Michael G. Kaplitt, Andrew Feigin, Chengke Tang et al. · The Lancet · 2007 · 1.1K citations

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Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Brian K. Kaspar, Jerònia Lladó, Nushin Sherkat et al. · Science · 2003 · 867 citations

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Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

Corinna Bürger, Oleg S. Gorbatyuk, Margaret J. Velardo et al. · Molecular Therapy · 2004 · 738 citations · Full text

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