Concepedia

Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels

Deeba N. Syed, Farrukh Afaq, Nityanand Maddodi, Jeremy J. Johnson, Sami Sarfaraz, Adeel Ahmad, Vijayasaradhi Setaluri, Hasan Mukhtar

Journal of Investigative Dermatology · 2011 · 168 citations · 14 references

DOIFull text

Open access

Concepts

References

14

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Levi A. Garraway, Hans R. Widlund, Mark A. Rubin et al. · Nature · 2005 · 1.5K citations

, , +15

Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity

Dexing Fang, David H. Hawke, Yanhua Zheng et al. · Journal of Biological Chemistry · 2007 · 874 citations · Full text

, , +17

β-Catenin–induced melanoma growth requires the downstream target <i>Microphthalmia</i>-associated transcription factor

Hans R. Widlund, Martin A. Horstmann, Edwin R. Price et al. · The Journal of Cell Biology · 2002 · 288 citations · Full text

, , +13

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma

Baskaran Govindarajan, James E. Sligh, Bethaney Vincent et al. · Journal of Clinical Investigation · 2007 · 272 citations · Full text

, , +14

The Microphthalmia-Associated Transcription Factor Mitf Interacts with β-Catenin To Determine Target Gene Expression

Alexander Schepsky, Katja Bruser, Gunnar J. Gunnarsson et al. · Molecular and Cellular Biology · 2006 · 187 citations

, , +17