AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation

The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial

David Grimwade, Helen M. Walker, Fiona Oliver et al. · Blood · 1998 · 2.6K citations · Full text

Life Sciences, Hematology, Oncology +12

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

María E. Figueroa, Sanne Lugthart, Yushan Li et al. · Cancer Cell · 2010 · 833 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia

Deborah Stroka, Tobias Burkhardt, Isabelle Desbaillets et al. · The FASEB Journal · 2001 · 720 citations · Full text

Medicine, Cell Biology, Molecular Biology +17

Adverse Prognostic Significance of <i>KIT</i> Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study

Peter Paschka, Guido Marcucci, Amy S. Ruppert et al. · Journal of Clinical Oncology · 2006 · 666 citations

Medicine, Hematology, Oncology +17

Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.

James G. Herman, Jin Jen, Adrian Merlo et al. · PubMed · 1996 · 578 citations

Medicine, Molecular Biology, Molecular Genetics +17