Concepedia

Controlled porosity solubility- and resin-modulated osmotic drug delivery systems for release of diltiazem hydrochloride

Gaylen M. Zentner, Gregory A. McClelland, Steven C. Sutton

Journal of Controlled Release · 1991 · 79 citations · 4 references

Concepts

PharmacyPharmaceuticsPharmacologyControlled Release FormulationsDrug DeliveryPharmaceutical FormulationControlled Release MechanismsDissolution-controlled ReleaseDrug Delivery EngineeringDrug Delivery SystemsDrug Release From Dosage FormsDrug Release KineticsDiltiazem TherapyLipophilic Drug SolubilizationOsmotically Controlled DissolutionPolymer Matrix OptimizationPolymer-based SolubilizationPorositySolubility

References

4

Elementary Osmotic Pump

Felix Theeuwes · Journal of Pharmaceutical Sciences · 1975 · 540 citations

The Solubility-Modulated Osmotic Pump: In Vitro/in Vivo Release of Diltiazem Hydrochloride

Gregory A. McClelland, Steven C. Sutton, Karen Engle et al. · Pharmaceutical Research · 1991 · 90 citations

Pharmacy, Pharmaceutics, Pharmacology +15

Osmotic flow through controlled porosity films: An approach to delivery of water soluble compounds

Gaylen M. Zentner, Gerald S. Rork, Kenneth J. Himmelstein · Journal of Controlled Release · 1985 · 87 citations

Engineering, Chemical Engineering, Materials Science +16

Mechanism of water transport in controlled porosity osmotic devices

Avinash G. Thombre, Gaylen M. Zentner, Kenneth J. Himmelstein · Journal of Membrane Science · 1989 · 29 citations

Engineering, Chemical Engineering, Materials Engineering +14