Concepedia

Polymer-based Solubilization

Polymer-Based Solubilization is a solubilization technique that employs water-soluble or amphiphilic polymers to enhance the apparent solubility and stability of poorly water-soluble drugs through molecular dispersion, hydrogen bonding, or micelle-like aggregation, distinguishing it from other solubilization methods by its reliance on polymeric carriers to modulate drug-polymer interactions in aqueous environments.

188

Publications

9.2K

Citations

789

Authors

265

Institutions

Publications per year

2017–2026

50

Parents

Publications

188

Structure and properties of pharmacologically active polymers

Helmut Ringsdorf · Journal of Polymer Science Polymer Symposia · 1975 · 1.1K citations

, , +11

Solubilization of fullerenes into water with polyvinylpyrrolidone applicable to biological tests

Yoko Yamakoshi, Takeshi Yagami, Kiyoshi Fukuhara et al. · Journal of the Chemical Society Chemical Communications · 1994 · 266 citations

, , +4

Soluplus®: A novel polymeric solubilizer for optimization of Carvedilol solid dispersions: Formulation design and effect of method of preparation

Rehab Nabil Shamma, Mona Basha · Powder Technology · 2012 · 256 citations

, , +16

Solubilization of hydrophobic drugs by methoxy poly(ethylene glycol)‐block‐polycaprolactone diblock copolymer micelles: Theoretical and experimental data and correlations

Kevin Letchford, Richard Liggins, Helen M. Burt · Journal of Pharmaceutical Sciences · 2007 · 253 citations

, , +15

Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation

Dorothée Le Garrec, Sandra Gori, Lan Luo et al. · Journal of Controlled Release · 2004 · 252 citations

, , +12

1–5 of 188

Authors

789

  1. RL
    Robert Luxenhofer

    University of Würzburg, Germany

    6 publications · 361 citations

    6

    h-index

  2. KI
    Kazuhíko Ishihara

    The University of Tokyo, Japan

    5 publications · 245 citations

    5

    h-index

  3. MM
    Michael M. Lübtow

    University of Würzburg, Germany

    4 publications · 311 citations

    4

    h-index

  4. TK
    Tomohiro Konno

    The University of Tokyo, Japan

    3 publications · 221 citations

    3

    h-index

  5. TY
    Takatsune Yoshida

    Astellas Pharma (Japan), Japan

    3 publications · 103 citations

    3

    h-index

1–5 of 789

Institutions

265

  1. Purdue University West Lafayette

    West Lafayette, United States

    5 h-index

    15 publications

    1.5K citations

  2. The University of Tokyo

    Tokyo, Japan

    5 h-index

    11 publications

    692 citations

  3. University of Würzburg

    Würzburg, Germany

    5 h-index

    31 publications

    1.7K citations

  4. Université de Montréal

    Montreal, Canada

    4 h-index

    14 publications

    1.5K citations

  5. Tokyo University of Science

    Tokyo, Japan

    4 h-index

    14 publications

    366 citations

  6. Dr. Hari Singh Gour University

    Saugor, India

    3 h-index

    3 publications

    190 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    8 publications

    124 citations

  8. Astellas Pharma (Japan)

    Tokyo, Japan

    3 h-index

    16 publications

    586 citations

1–8 of 265

Venues

  1. Journal of Pharmaceutical Sciences

    11 publications · 736 citations

    10

    h-index

  2. Drug Development and Industrial Pharmacy

    10 publications · 334 citations

    10

    h-index

  3. Biomacromolecules

    7 publications · 609 citations

    7

    h-index

  4. International Journal of Pharmaceutics

    6 publications · 298 citations

    6

    h-index

  5. PubMed

    Repository · 6 publications · 250 citations

    6

    h-index

1–5