Determination of Parameters Responsible for Pharmacokinetic Behavior of TCDD in Female Sprague–Dawley Rats

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

Alan Poland, Edward Glover, Andrew S. Kende · Journal of Biological Chemistry · 1976 · 1.4K citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

R.J. Kociba, D. G. Keyes, J Beyer et al. · Toxicology and Applied Pharmacology · 1978 · 1.1K citations

Pharmacy, Environmental Sciences, Toxicology +9

Receptors; models for binding, trafficking and signaling

General Pharmacology The Vascular System · 1997 · 871 citations

Life Sciences, Biochemistry, Molecular Biology +10

Comparison of four basic models of indirect pharmacodynamic responses

Natalie Dayneka, Varun Garg, William J. Jusko · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 811 citations

Medicine, Pharmacokinetics, Pharmacology +14

The pharmacokinetics of Norpace.

Aziz Karim · PubMed · 1975 · 555 citations

Pharmacy, Pharmacokinetics, Pharmacology +4