Concepedia

Pharmacokinetic Parameter Selection

Pharmacokinetic Parameter Selection is the systematic process of identifying and justifying specific pharmacokinetic metrics—such as Cmax, AUC, and tmax—for use in the design and evaluation of bioequivalence studies based on their scientific relevance, regulatory acceptability, and ability to reflect the rate and extent of drug absorption.

125

Publications

7.6K

Citations

633

Authors

267

Institutions

Publications per year

2017–2026

21

Parents

Publications

125

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 646 citations

, , +11

Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules

Binodh DeSilva, Wendell C. Smith, Russell Weiner et al. · Pharmaceutical Research · 2003 · 614 citations

, , +14

Clinical Pharmacodynamics of Meropenem in Patients with Lower Respiratory Tract Infections

Chonghua Li, Xiaoli Du, Joseph L. Kuti et al. · Antimicrobial Agents and Chemotherapy · 2007 · 292 citations

, , +17

Pharmacokinetics of Fentanyl Administered by Computer-controlled Infusion Pump

Steven L. Shafer, John R. Varvel, Natasha Aziz et al. · Anesthesiology · 1990 · 284 citations · Full text

, , +13

Pharmacokinetic Model Selection for Target Controlled Infusions of Propofol

J. F. Coetzee, J. B. Glen, L. Boshoff · Anesthesiology · 1995 · 257 citations · Full text

, , +15

1–5 of 125

Authors

633

  1. ZJ
    Zheng Jiao

    Huashan Hospital, China

    2 publications · 44 citations

    2

    h-index

  2. BW
    Bo Wu

    Shenyang Pharmaceutical University, China

    2 publications · 44 citations

    2

    h-index

  3. PK
    Peter Kletting

    Universität Ulm, Germany

    2 publications · 262 citations

    2

    h-index

  4. EI
    Ennio Imbimbo

    Mario Negri Institute for Pharmacological Research, Italy

    2 publications · 68 citations

    2

    h-index

  5. GG
    Gerhard Glatting

    Universität Ulm, Germany

    2 publications · 262 citations

    2

    h-index

1–5 of 633

Institutions

267

  1. University of California, San Francisco

    San Francisco, United States

    4 h-index

    8 publications

    489 citations

  2. Erasmus MC

    Rotterdam, The Netherlands

    4 h-index

    13 publications

    480 citations

  3. Center for Drug Evaluation and Research

    Silver Spring, United States

    4 h-index

    24 publications

    753 citations

  4. Inserm

    Paris, France

    3 h-index

    9 publications

    257 citations

  5. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    3 h-index

    9 publications

    270 citations

  6. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    3 h-index

    16 publications

    227 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    3 h-index

    10 publications

    177 citations

  8. University of Toronto

    Toronto, Canada

    3 h-index

    6 publications

    484 citations

1–8 of 267

Venues

  1. Pharmaceutical Research

    10 publications · 886 citations

    10

    h-index

  2. PubMed

    Repository · 7 publications · 384 citations

    7

    h-index

  3. Journal of Pharmacokinetics and Biopharmaceutics

    6 publications · 1.1K citations

    6

    h-index

  4. Journal of Pharmaceutical Sciences

    5 publications · 233 citations

    5

    h-index

  5. Cancer Chemotherapy and Pharmacology

    5 publications · 141 citations

    5

    h-index

1–5