Concepedia

Accelerated discovery via a whole-cell model

Jayodita C. Sanghvi, Sergi Regot, Silvia Carrasco, Jonathan R. Karr, Miriam V. Gutschow, Benjamin Bolival, Markus W. Covert

Nature Methods · 2013 · 71 citations · 15 references

DOIFull text

Open access

Concepts

References

15

Enzymatic assembly of DNA molecules up to several hundred kilobases

Daniel G. Gibson, Lei Young, Ray-Yuan Chuang et al. · Nature Methods · 2009 · 10.6K citations

, , +9

What is flux balance analysis?

Jeffrey D. Orth, Ines Thiele, Bernhard Ø. Palsson · Nature Biotechnology · 2010 · 4K citations

, , +5

A Whole-Cell Computational Model Predicts Phenotype from Genotype

Jonathan R. Karr, Jayodita C. Sanghvi, Derek N. Macklin et al. · Cell · 2012 · 1.3K citations

, , +5

Essential genes of a minimal bacterium

John I. Glass, Nacyra Assad-Garcia, Nina Alperovich et al. · Proceedings of the National Academy of Sciences · 2006 · 896 citations · Full text

, , +15

Integrating high-throughput and computational data elucidates bacterial networks

Markus W. Covert, Eric M. Knight, Jennifer L. Reed et al. · Nature · 2004 · 792 citations

, , +7