Jonathan R. Karr

A Whole-Cell Computational Model Predicts Phenotype from Genotype

Jonathan R. Karr, Jayodita C. Sanghvi, Derek N. Macklin et al. · Cell · 2012 · 1.3K citations

Allelic Variant, Genotype-phenotype Association, Genetics +5

Integrating metabolic, transcriptional regulatory and signal transduction models in<i>Escherichia coli</i>

Markus W. Covert, Nan Xiao, Tiffany J. Chen et al. · Bioinformatics · 2008 · 315 citations · Full text

A blueprint for human whole-cell modeling

Balázs Szigeti, Yosef D. Roth, John A. P. Sekar et al. · Current Opinion in Systems Biology · 2017 · 78 citations · Full text

Engineering, Medicine, Computational Biology +6

Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models

Jonathan R. Karr, Jeremy Zucker, Andreas Raue et al. · PLoS Computational Biology · 2015 · 73 citations · Full text

Parameter Estimation, Engineering, Genomics +22

Accelerated discovery via a whole-cell model

Jayodita C. Sanghvi, Sergi Regot, Silvia Carrasco et al. · Nature Methods · 2013 · 71 citations · Full text

Discovery Technique, Engineering, Medicine +6