Concepedia

Development of the polymer micelle carrier system for doxorubicin

Takeshi Nakanishi, Shigeto Fukushima, Kazuya Okamoto, Masanobu Suzuki, Yasuhiro Matsumura, M. Yokoyama, Teruo Okano, Yu Sakurai, Kazunori Kataoka

Journal of Controlled Release · 2001 · 566 citations · 12 references

DOI

Concepts

References

12

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

, , +12

Formation of Polyion Complex Micelles in an Aqueous Milieu from a Pair of Oppositely-Charged Block Copolymers with Poly(ethylene glycol) Segments

Atsushi Harada, Kazunori Kataoka · Macromolecules · 1995 · 836 citations

, , +17

Chain Length Recognition: Core-Shell Supramolecular Assembly from Oppositely Charged Block Copolymers

Atsushi Harada, Kazunori Kataoka · Science · 1999 · 590 citations

, , +16

Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood.

M. Yokoyama, Teruo Okano, Yoshinori Sakurai et al. · PubMed · 1991 · 418 citations

, , +14

Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly (ethylene oxide-aspartate) block copolymer-adriamycin conjugates

Glen S. Kwon, Satoru Suwa, M. Yokoyama et al. · Journal of Controlled Release · 1994 · 409 citations

, , +17