Nucleic Acids Research · 1980 · 364 citations · 68 references
Life SciencesGeneticsMolecular GeneticsComparative GenomicsGenomicsSequence AnalysisCodon EvolutionGenetic CodeGenomic VariationAmino AcidsCodingCodon DegeneracyCodon Evolution In Protein-coding GenesCodon Usage BiasCodon Usage EvolutionRelative Synonymous Codon UsageSynonymous Codon Choice
The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.
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Nucleotide sequence of bacteriophage G4 DNA
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