Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type

Richard Grantham, Christian Gautier, Manolo Gouy

Nucleic Acids Research · 1980 · 363 citations · 68 references

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Abstract

The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.

References

68