Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

Scott A. Armstrong, Jane Staunton, Lewis B. Silverman et al. · Nature Genetics · 2001 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +16

The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers

Masataka Ohta, Hiroshi Inoue, M. Grazia Cotticelli et al. · Cell · 1996 · 997 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor

Luciano Di Croce, Veronica A. Raker, Massimo Corsaro et al. · Science · 2002 · 780 citations

Medicine, Genetics, Molecular Biology +17

Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots

Karin B. Gale, Anthony M. Ford, Reinald Repp et al. · Proceedings of the National Academy of Sciences · 1997 · 564 citations

Life Sciences, Genetics, Molecular Biology +17

Biological and therapeutic aspects of infant leukemia

Andrea Biondi, Giuseppe Cimino, Rob Pieters et al. · Blood · 2000 · 402 citations

Medicine, Hematology, Oncology +14