Biological and therapeutic aspects of infant leukemia

Abstract

Leukemias diagnosed in the first 12 months of life are characterized by an equal distribution of lymphoid and myeloid subtypes and account for 2.5% to 5% of acute lymphoblastic leukemias (ALLs) and 6% to 14% of acute myeloid leukemias (AMLs) of childhood.[1][1] [2][2] In contrast to an excess of