Concepedia

Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites

Satoshi Komoriya, Naoaki Kanaya, Takayasu Nagahara, Asako Yokoyama, Kazue Inamura, Yukio Yokoyama, SHINICHI KATAKURA, Tsuyoshi Hara

Bioorganic & Medicinal Chemistry · 2004 · 15 citations · 5 references

DOI

Concepts

References

5

X-ray Structure of Active Site-inhibited Clotting Factor Xa

Hans Brandstetter, Anja Kühne, Wolfram Bode et al. · Journal of Biological Chemistry · 1996 · 278 citations · Full text

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Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors

Takayasu Nagahara, Yukio Yokoyama, Kazue Inamura et al. · Journal of Medicinal Chemistry · 1994 · 178 citations · Full text

, , +15

The Preparation of Orthoesters

S. M. McElvain, J. Walter Nelson · Journal of the American Chemical Society · 1942 · 106 citations

, , +5

348. The preparation of benziminazoles and benzoxazoles from Schiff's bases. Part II

F. F. Stephens, J. D. Bower · Journal of the Chemical Society (Resumed) · 1950 · 54 citations

, , +5

The ideal anti-thrombotic drug

Jan J. Sixma, Ph.G. de Groot · Thrombosis Research · 1992 · 21 citations

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