Three practical approaches for the synthesis of novel 4,7-dihetarylpyrazolo[1,5-a][1,3,5]triazines

Structure-Based Discovery of A _2A Adenosine Receptor Ligands

Jens Carlsson, Lena S. Yoo, Zhan-Guo Gao et al. · Journal of Medicinal Chemistry · 2010 · 222 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors

E. Ongini, Silvio Dionisotti, Stefania Gessi et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1999 · 185 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2

Zhe Nie, Carin Perretta, Philip Erickson et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 97 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

An efficient synthesis of pyrazolo[3,4-b]pyridine-4-spiroindolinones by a three-component reaction of 5-aminopyrazoles, isatin, and cyclic β-diketones

Jairo Quiroga, Sandra Portillo, Alfredo Pérez et al. · Tetrahedron Letters · 2011 · 97 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities

Zhe Nie, Carin Perretta, Philip Erickson et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 97 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16