Differential effects of regulator of G protein signaling (RGS) proteins on serotonin 5-HT1A, 5-HT2A, and dopamine D2 receptor-mediated signaling and adenylyl cyclase activity

Crystal Structure of the Catalytic Domains of Adenylyl Cyclase in a Complex with G _sα ·GTPγS

J.J.G. Tesmer, Roger K. Sunahara, Alfred G. Gilman et al. · Science · 1997 · 811 citations

Life Sciences, Biochemistry, Molecular Biology +17

Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

Boris Ν. Kholodenko, Anatoly Kiyatkin, Frank J. Bruggeman et al. · Proceedings of the National Academy of Sciences · 2002 · 436 citations · Full text

Life Sciences, Cell Biology, Systems Biology +17

RGS2/G0S8 is a selective inhibitor of Gqα function

Scott P. Heximer, Ned Watson, Maurine E. Linder et al. · Proceedings of the National Academy of Sciences · 1997 · 347 citations

Life Sciences, Molecular Biology, Pharmacology +13

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

Tatsuya Ingi, Andrejs M. Krumins, Peter Chidiac et al. · Journal of Neuroscience · 1998 · 298 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Effector Coupling Mechanisms of the Cloned 5-HT1A Receptor

A. Fargin, John R. Raymond, John W. Regan et al. · Journal of Biological Chemistry · 1989 · 274 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +15