Inhibitory Function of Two NFAT Family Members in Lymphoid Homeostasis and Th2 Development

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

Rie Watanabe‐Fukunaga, Camilynn I. Brannan, Neal G. Copeland et al. · Nature · 1992 · 2.9K citations

Life Sciences, Immunology, Pathology +14

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text

Life Sciences, Immunology, Pathology +14

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.4K citations · Full text

Life Sciences, Genetics, Immunology +17

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Neil A. Clipstone · Nature · 1992 · 1.6K citations

Life Sciences, Immunology, Molecular Biology +12

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

Tomohiro Takahashi, Masato Tanaka, Camllynn I. Brannan et al. · Cell · 1994 · 1.5K citations

Life Sciences, Immunology, Pathology +12