Science · 1975 · 456 citations · 9 references
Veterinary MedicineBiologyInfectious DiseasesBiomedical OpticsBiophotonicsParasitologyBlood ParasitesHost Cell InvasionLight MicroscopyMalariaParasite SpreadParasite TransmissionBlood-stage Malaria PathogenesisHigh-resolution ImagingMalaria MicroscopyMerozoite MorphologyMicroscope ImagingMicroscopic Visualization Of Parasites
An electro-optical system was developed to record microscope images with high resolution at low light intensities. The system was used to study the invasion of erythrocytes by malaria merozoites. Invasion consists of attachment of the anterior end of the parasite to the erythrocyte, deformation of the erythrocyte, and the entry of the parasite by erythrocyte membrane invagination.
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