The immune response to a DNA vaccine can be modulated by co-delivery of cytokine genes using a DNA prime-protein boost strategy

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

Gunther Hartmann, George J. Weiner, A M Krieg · Proceedings of the National Academy of Sciences · 1999 · 624 citations

Life Sciences, Immunology, Molecular Biology +17

Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines

Zhiquan Xiang, Hildegund C.J. Ertl · Immunity · 1995 · 480 citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

Maripat Corr, D J Lee, Dennis A. Carson et al. · The Journal of Experimental Medicine · 1996 · 478 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

DNA Vaccination:  Transfection and Activation of Dendritic Cells as Key Events for Immunity

Omid Akbari, Naveed Panjwani, Sylvie Garcia et al. · The Journal of Experimental Medicine · 1999 · 362 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus

Stephen J. Kent, Anne Zhao, Susan J. Best et al. · Journal of Virology · 1998 · 325 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17