Concepedia

Fragment Based Approach for the Investigation of HIV-1 Integrase Inhibition

Jarosław Polański, Halina Niedbala, Barbara Podeszwa, D. Tabak, Anna Palka, Agnieszka Mencel, Jean‐François Mouscadet, Marc Le Bret

Letters in Drug Design & Discovery · 2007 · 31 citations · 0 references

Concepts

PharmacyChemistryMedicinal ChemistryDrug DesignDrug DiscoveryStructure-activity RelationshipsAntiretroviral TherapyAntiviral AgentsAntiviral PharmacologyEnzyme InhibitionFragment-based Drug DesignLigand BindingAntiviral Structure-activity RelationshipsChemical Structure-activity RelationshipsIntegrase ProteinsIntegrase Strand Transfer InhibitorsNucleoside Reverse Transcriptase InhibitorsQuinoline ChemistryViral Entry Inhibitors