Jean‐François Mouscadet

Mutations Associated with Failure of Raltegravir Treatment Affect Integrase Sensitivity to the Inhibitor In Vitro

Isabelle Malet, Olivier Delelis, Marc‐Antoine Valantin et al. · Antimicrobial Agents and Chemotherapy · 2008 · 280 citations · Full text

Life Sciences, Infectious Diseases, Pharmacotherapy +17

Styrylquinoline Derivatives:  A New Class of Potent HIV-1 Integrase Inhibitors That Block HIV-1 Replication in CEM Cells

Khalid Mekouar, Jean‐François Mouscadet, Didier Desmaële et al. · Journal of Medicinal Chemistry · 1998 · 223 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections

M. Fakhfakh, Alain Fournet, Eric Prina et al. · Bioorganic & Medicinal Chemistry · 2003 · 195 citations

Pharmacy, Infectious Diseases, Medicinal Chemistry +17

Structure−Activity Relationships and Binding Mode of Styrylquinolines as Potent Inhibitors of HIV-1 Integrase and Replication of HIV-1 in Cell Culture

Fatima Zouhiri, Jean‐François Mouscadet, Khalid Mekouar et al. · Journal of Medicinal Chemistry · 2000 · 148 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Relationship between the Oligomeric Status of HIV-1 Integrase on DNA and Enzymatic Activity

Elvire Guiot, Kévin Carayon, Olivier Delelis et al. · Journal of Biological Chemistry · 2006 · 142 citations · Full text

Life Sciences, Biochemistry, Biology +13