Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Mihael H. Polymeropoulos, Christian Lavedan, Elisabeth Leroy et al. · Science · 1997 · 8.2K citations

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Johan Skog, Tom Würdinger, Sjoerd van Rijn et al. · Nature Cell Biology · 2008 · 4.9K citations

Neuro-oncology, Glioma, Tumour Growth +10

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

Brendan MacLean, Daniela M. Tomazela, Nicholas Shulman et al. · Bioinformatics · 2010 · 4.8K citations · Full text

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology · 2011 · 4.7K citations

Cell-based Drug Delivery, Nanomedicine, Systemic Injection +9

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Javier Simón‐Sánchez, Claudia Schulte, José Brás et al. · Nature Genetics · 2009 · 1.9K citations · Full text

Genome-wide Association Study, Genetics, Genetic Epidemiology +6