Concepedia

A novel mutation within the extracellular domain of TrkA causes constitutive receptor activation

Juan Carlos Arévalo, Blanca Conde, Barbara Hempstead, Moses V. Chao, Dionisio Martı́n-Zanca, Pilar Pérez

Oncogene · 2001 · 54 citations · 26 references

DOI

Concepts

References

26

Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome

Andrew O.M. Wilkie, Sarah F. Slaney, Michael Oldridge et al. · Nature Genetics · 1995 · 937 citations

, , +7

A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome

Maximilian Muenke, Ute Schell, Andreas Hehr et al. · Nature Genetics · 1994 · 623 citations

, , +10

Structural Basis for FGF Receptor Dimerization and Activation

A.N. Plotnikov, Joseph Schlessinger, Stevan R. Hubbard et al. · Cell · 1999 · 606 citations · Full text

, , +17

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

Christian Wiesmann, Mark Ultsch, Steven Bass et al. · Nature · 1999 · 410 citations

, , +17

Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity

A.N. Plotnikov, Stevan R. Hubbard, Joseph Schlessinger et al. · Cell · 2000 · 409 citations · Full text

, , +16