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A Possible Mechanistic Link Between the CYP2C19 Genotype, the Methadone Metabolite Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidene (EDDP), and Methadone-Induced Corrected QT Interval Prolongation in a Pilot Study

John F. Carlquist, David E. Moody, Stacey Knight, Eric Johnson, Wenfang B. Fang, John Huntinghouse, Jeffrey Rollo, Lynn R. Webster, Jeffrey L. Anderson

Molecular Diagnosis & Therapy · 2015 · 29 citations · 23 references

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References

23

Genome-wide association study identifies eight loci associated with blood pressure

Christopher Newton‐Cheh, Toby Johnson, Vesela Gateva et al. · Nature Genetics · 2009 · 1.2K citations · Full text

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Prolonged QTc Interval and Risk of Sudden Cardiac Death in a Population of Older Adults

Sabine M. J. M. Straus, Jan A. Kors, Marie L. De Bruin et al. · Journal of the American College of Cardiology · 2006 · 821 citations

, , +16

Torsade de Pointes Associated with Very-High-Dose Methadone

Mori J. Krantz, Laurent Lewkowiez, Helen Hays et al. · Annals of Internal Medicine · 2002 · 421 citations

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

Arne Pfeufer, Serena Sanna, Dan E. Arking et al. · Nature Genetics · 2009 · 391 citations · Full text

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QTc Interval Screening in Methadone Treatment

Mori J. Krantz · Annals of Internal Medicine · 2009 · 331 citations