Enhanced transformation and chemosensitivity of NIH3T3 cells transduced with hepatoma up-regulated protein

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.8K citations

Medicine, Genetics, Oncology +14

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed · 1988 · 2.4K citations

Medicine, Oncology, Pharmacology +9

Action of 2',2'-difluorodeoxycytidine on DNA synthesis.

Peng Huang, Sherri Chubb, Larry W. Hertel et al. · PubMed · 1991 · 884 citations

Life Sciences, Genetics, Molecular Biology +11

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.

Volker Heinemann, Larry W. Hertel, Gerald B. Grindey et al. · PubMed · 1988 · 509 citations

Medicine, Pharmacokinetics, Pharmacology +13

Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.

Volker Heinemann, Yi-Zheng Xu, Sherri Chubb et al. · Molecular Pharmacology · 1990 · 407 citations

Life Sciences, Biochemistry, Molecular Biology +13