Concepedia

G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress

Christine Didier, Cindy Cavelier, Muriel Quaranta, M-O Galcera, Cécile Demur, Stéphane Manenti, Bernard Ducommun

Oncogene · 2008 · 38 citations · 34 references

DOI

Concepts

References

34

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

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The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01

Paul R. Graves, Lijia Yu, Julie K. Schwarz et al. · Journal of Biological Chemistry · 2000 · 541 citations · Full text

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Two Molecularly Distinct G<sub>2</sub>/M Checkpoints Are Induced by Ionizing Irradiation

Bo Xu, Seong‐Tae Kim, Dae‐Sik Lim et al. · Molecular and Cellular Biology · 2002 · 474 citations · Full text

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Claspin, a Novel Protein Required for the Activation of Chk1 during a DNA Replication Checkpoint Response in Xenopus Egg Extracts

Akiko Kumagai, William G. Dunphy · Molecular Cell · 2000 · 426 citations · Full text

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Polo-like Kinase-1 Controls Recovery from a G2 DNA Damage-Induced Arrest in Mammalian Cells

Marcel A.T.M. van Vugt, Alexandra Le Bras, René H. Medema · Molecular Cell · 2004 · 378 citations · Full text

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