Concepedia

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis

Mirella Trinei, Marco Giorgio, Angelo Cicalese, Sara Barozzi, Andrea Ventura, Enrica Migliaccio, Elisabetta Milia, Ines Martin Padura, Veronica A. Raker, Marco Maccarana,

Oncogene · 2002 · 437 citations · 17 references

DOI

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17

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

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A model for p53-induced apoptosis

Kornélia Polyák, Yong Xia, Jay L. Zweíer et al. · Nature · 1997 · 2.5K citations

, , +12

The aging process.

Denham Harman · Proceedings of the National Academy of Sciences · 1981 · 1.9K citations · Full text

, , +17

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

F. Michael Yakes, Bennett Van Houten · Proceedings of the National Academy of Sciences · 1997 · 1.8K citations

, , +15

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Enrica Migliaccio, Marco Giorgio, Simonetta Mele et al. · Nature · 1999 · 1.7K citations

, , +16