Tricyclononene carboxamide derivatives as novel anti-HIV-1 agents

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

Richard D. Cramer, David E. Patterson, Jeffrey D. Bunce · Journal of the American Chemical Society · 1988 · 3.9K citations

Life Sciences, Biochemistry, Pharmacology +14

An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Guang Yang, Daniel C. Pevear, Marc H. Davies et al. · Journal of Virology · 2005 · 457 citations · Full text

Life Sciences, Infectious Diseases, Host-pathogen Interactions +12

Maximally diagonal force constants in dependent angle-bending coordinates. II. Implications for the design of empirical force fields

Thomas A. Halgren · Journal of the American Chemical Society · 1990 · 166 citations

Natural Sciences, Physics, Electromagnetism +7

Structure-Based Identification of Small Molecule Antiviral Compounds Targeted to the gp41 Core Structure of the Human Immunodeficiency Virus Type 1

Asim K. Debnath, Lin Radigan, Shibo Jiang · Journal of Medicinal Chemistry · 1999 · 164 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

A novel assay for the DNA strand-transfer reaction of HIV-1 integrase

Daria J. Hazuda, Jeffrey C. Hastings, Abigail Wolfe et al. · Nucleic Acids Research · 1994 · 118 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12