Autophagy is required for necrotic cell death in Caenorhabditis elegans

THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>

Sydney Brenner · Genetics · 1974 · 15.5K citations · Full text

Life Sciences, Biology, Genetics +14

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

Sophie Pattingre, Amina Tassa, Xueping Qu et al. · Cell · 2005 · 3.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +8

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

Life Sciences, Genetics, Neuroscience +17