Journal of the Chemical Society C Organic · 1968 · 23 citations · 0 references
PharmacyBiochemistryChemistryNucleic Acid BiochemistryNucleic Acid ChemistryOrganic ChemistryDna ChemistryNucleic Acid ModificationNucleic Acid StructureNucleobase ChemistryRibonucleic Acid (Rna) ChemistryModified NucleobasesNucleoside AnalogsNucleoside ModificationNucleotide AnalogsPurine ChemistryPyrimidine AnalogsPyrimidine AnaloguesPyrimidine Chemistry
Cytidine, adenosine, and guanosine were treated with benzyl bromide; the stability of the products to acid and to alkali was compared with the stability of the corresponding methyl derivatives. 1-Benzyladenine was much less stable than 1-methyladenine in hot acid and readily underwent fission of the pyrimidine ring with loss of C-2.