Angiotensin II regulates phosphoinositide 3 kinase/Akt cascade via a negative crosstalk between AT1 and AT2 receptors in skin fibroblasts of human hypertrophic scars

The PI3K–PDK1 connection: more than just a road to PKB

Bart Vanhaesebroeck, Dario R. Alessi · Biochemical Journal · 2000 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors.

Xiaoping Yang, Victor G. Sharov, Omar Nass et al. · Journal of Clinical Investigation · 1997 · 604 citations · Full text

Medicine, Cardiology, Pharmacology +17

Calcium-dependent Epidermal Growth Factor Receptor Transactivation Mediates the Angiotensin II-induced Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells

Satoru Eguchi, Kotaro Numaguchi, Hiroaki Iwasaki et al. · Journal of Biological Chemistry · 1998 · 566 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +16

Circulating versus local renin-angiotensin system in cardiovascular homeostasis.

Victor J. Dzau · PubMed · 1988 · 476 citations

Medicine, Pharmacology, Physiology +14

Insulin Prevents Cardiomyocytes From Oxidative Stress–Induced Apoptosis Through Activation of PI3 Kinase/ <i>Akt</i>

Ryuichi Aikawa, Masao Nawano, Yaping Gu et al. · Circulation · 2000 · 226 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17