Concepedia

Scar Pathophysiology

Scar Pathophysiology is a pathophysiological framework that delineates the biological mechanisms and structural alterations underlying abnormal scar formation following thermal injury, distinguishing it from general wound healing processes by its focus on dysregulated collagen deposition, excessive fibroblast activity, and chronic inflammation specific to burn-induced tissue repair.

537

Publications

27.8K

Citations

2.5K

Authors

727

Institutions

Publications per year

2017–2026

141

Parents

Publications

537

Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment

Brian Berman, Andrea D. Maderal, Brian A. Raphael · Dermatologic Surgery · 2016 · 669 citations

, , +17

Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis

Shahram Aarabi, Kirit A. Bhatt, Yubin Shi et al. · The FASEB Journal · 2007 · 503 citations

, , +17

Regulated Production of Type I Collagen and Inflammatory Cytokines by Peripheral Blood Fibrocytes

Jason Chesney, Christine N. Metz, Abram B. Stavitsky et al. · The Journal of Immunology · 1998 · 374 citations · Full text

, , +17

Expression of the Gene Encoding the Chemorepellent Semaphorin III Is Induced in the Fibroblast Component of Neural Scar Tissue Formed Following Injuries of Adult But Not Neonatal CNS

R. Jeroen Pasterkamp, Roman J. Giger, Marc J. Ruitenberg et al. · Molecular and Cellular Neuroscience · 1999 · 311 citations

, , +17

Characterization of the collagen of human hypertrophic and normal scars

Allen J. Bailey, S Bazin, Trevor J. Sims et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure · 1975 · 291 citations

, , +12

1–5 of 537

Authors

2.5K

  1. EE
    Edward E. Tredget

    University of Alberta, Canada

    24 publications · 1.9K citations

    23

    h-index

  2. MS
    Maurizio Stella

    CTO Hospital, Italy

    12 publications · 520 citations

    12

    h-index

  3. PG
    Paul G. Scott

    University of Alberta, Canada

    12 publications · 1K citations

    12

    h-index

  4. JD
    Jie Ding

    University of Alberta, Canada

    11 publications · 808 citations

    11

    h-index

  5. DH
    Dahai Hu

    Xijing Hospital, China

    10 publications · 333 citations

    10

    h-index

1–5 of 2.5K

Institutions

727

  1. University of Alberta

    Edmonton, Canada

    24 h-index

    114 publications

    9.2K citations

  2. Shriners Hospitals for Children - Galveston

    Galveston, United States

    16 h-index

    67 publications

    3.1K citations

  3. University of Manchester

    Manchester, United Kingdom

    13 h-index

    43 publications

    3.6K citations

  4. Shanghai Jiao Tong University

    Shanghai, China

    13 h-index

    84 publications

    2.6K citations

  5. Northwestern University

    Evanston, United States

    12 h-index

    41 publications

    2.2K citations

  6. Shanghai Ninth People's Hospital

    Shanghai, China

    12 h-index

    72 publications

    2K citations

  7. Air Force Medical University

    Xi'an, China

    11 h-index

    98 publications

    3.3K citations

  8. Xijing Hospital

    Xi’an, China

    10 h-index

    89 publications

    3K citations

1–8 of 727

Venues

  1. Burns

    58 publications · 2.8K citations

    30

    h-index

  2. Wound Repair and Regeneration

    37 publications · 1.8K citations

    23

    h-index

  3. PubMed

    Repository · 32 publications · 1.2K citations

    18

    h-index

  4. Plastic & Reconstructive Surgery

    19 publications · 1.4K citations

    18

    h-index

  5. Journal of Investigative Dermatology

    JID · 17 publications · 1.4K citations

    17

    h-index

1–5