A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

Jianguo Xia, Nikolaos Psychogios, N. Young et al. · Nucleic Acids Research · 2009 · 2.3K citations · Full text

Akt Stimulates Aerobic Glycolysis in Cancer Cells

Rebecca Elstrom, Daniel E. Bauer, Monica Buzzai et al. · Cancer Research · 2004 · 1.4K citations

Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst

Jianguo Xia, David S. Wishart · Nature Protocols · 2011 · 1.3K citations

Metabolic Network, Systems Biology, Engineering +13

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou, George Poulogiannis, John M. Asara et al. · Science · 2011 · 1.2K citations · Full text

Lipid Peroxidation, Cell Death, Metabolic Remodeling +19

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

Biochemistry, Phosphoglycerate Dehydrogenase, Catabolism +4