Sigma receptors are expressed in human non-small cell lung carcinoma

A proposal for the classification of sigma binding sites

Rémi Quirion, Wayne D. Bowen, Yossef Itzhak et al. · Trends in Pharmacological Sciences · 1992 · 754 citations

Pharmacy, Molecular Biology, Molecular Recognition +7

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.

Bertold J. Vilner, Christy S. John, W D Bowen · PubMed · 1995 · 488 citations

Medicine, Oncology, Pharmacology +10

A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain

Susan B. Hellewell, W. Don Bowen · Brain Research · 1990 · 388 citations

Medicine, Neuroscience, Pharmacology +8

Overexpression of sigma receptors in nonneural human tumors.

Gail E. Thomas, James Y. Mamone, Sharon M. Homan et al. · PubMed · 1991 · 142 citations

Medicine, Oncology, Pharmacology +10

A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.

Christy S. John, W. Don Bowen, T. Saga et al. · PubMed · 1993 · 97 citations

Medicine, Oncology, Pharmacology +17