Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 Response

Decoding the Patterns of Self and Nonself by the Innate Immune System

Ruslan Medzhitov, Charles A. Janeway · Science · 2002 · 2.2K citations

Life Sciences, Evolutionary Biology, Immunology +17

TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

Felix Yarovinsky, Dekai Zhang, John F. Andersen et al. · Science · 2005 · 1K citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

Caetano Reis e Sousa, Sara Hieny, Tanya Scharton‐Kersten et al. · The Journal of Experimental Medicine · 1997 · 913 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

Kelly D. Smith, Erica Andersen‐Nissen, Fumitaka Hayashi et al. · Nature Immunology · 2003 · 813 citations

Life Sciences, Immunology, Microbiology +14

Toxoplasma Invasion of Mammalian Cells Is Powered by the Actin Cytoskeleton of the Parasite

Janice M. Dobrowolski, L. David Sibley · Cell · 1996 · 651 citations · Full text

Life Sciences, Cell Biology, Microbiology +13