Gender- or age-related binding characteristics of valproic acid to serum proteins in adult patients with epilepsy

Serum albumin: recent progress in the understanding of its structure and biosynthesis.

Theodore Peters · Clinical Chemistry · 1977 · 164 citations

Life Sciences, Biochemistry, Molecular Biology +14

The new generation of antiepileptic drugs: advantages and disadvantages

Emilio Perucca · British Journal of Clinical Pharmacology · 1996 · 126 citations

Medicine, Pharmacology, Pharmacotherapy +13

Effect of aging and cigarette smoking on antipyrine and indocyanine green elimination

Andrew J. Wood, Robert E. Vestal, G. Wilkinson et al. · Clinical Pharmacology & Therapeutics · 1979 · 123 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Valproic acid in the perinatal period: Decreased maternal serum protein binding results in fetal accumulation and neonatal displacement of the drug and some metabolites

Heinz Nau, H Helge, W. A. P. Luck · The Journal of Pediatrics · 1984 · 110 citations

Medicine, Obstetrics, Pharmacology +17

Valproic acid clearance: Unbound fraction and diurnal variation in young and elderly adults

Larry A. Bauer, Robin L. Davis, Alan J. Wilensky et al. · Clinical Pharmacology & Therapeutics · 1985 · 106 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +17