Concepedia
European Journal of Medicinal Chemistry · 2012 · 204 citations · 26 references
Medicinal ChemistryDerivative (Chemistry)EngineeringHeterocyclicMedicineDrug DiscoveryChemical DerivativeOrganic ChemistryHydantoin MoietiesHeterocycle ChemistryPharmacology2H-chromene DerivativesPharmaceutical ChemistryBiomolecular EngineeringPotential Anticancer Agents
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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations
Cellular Growth, Rapid Colorimetric Assay, Cytotoxicity Assays +11
Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin
Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text
Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16
Thiazolidenediones Mediate Apoptosis in Prostate Cancer Cells in Part through Inhibition of Bcl-xL/Bcl-2 Functions Independently of PPARγ
Chung-Wai Shiau, Chih-Cheng Yang, Samuel K. Kulp et al. · Cancer Research · 2005 · 216 citations
Chemoprevention Strategy, Apoptosis, Cell Death +18
Peroxisome Proliferator-Activated Receptor γ-Independent Ablation of Cyclin D1 by Thiazolidinediones and Their Derivatives in Breast Cancer Cells
Jui-Wen Huang, Chung-Wai Shiau, Ya-Ting Yang et al. · Molecular Pharmacology · 2005 · 117 citations
Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein
Wei Keat Ng, Latifah Saiful Yazan, Maznah Ismail · Toxicology in Vitro · 2011 · 105 citations
Nigella Sativa, Medicine, Apoptosis +7